By default Windows setups want to install in C:\Program Files\.... which is located in ~/.wine/drive_c/Program Files/K-Meleon, for example
To be able to use it with different users, I personnally created a folder named 'Program Files' in /opt
I have done it in sudo (sudo nautilus /opt)
I have changed rights to the user, and for groups to 'users', and I have checked to applicate it to all the files and folders under Program Files
I have too added a drive in wine E: in /opt
So when the setups ask for a path, I just modify C: to E:, and it installs in /opt/Program Files/K-Meleon (for example)
It now easy from setups to install windows programs. The only ennoying point is that in line command you must give the path in "path" or 'path' because of space. Linux accept to replace space by \'space', and "" or '' are no more needed.
I use the same K-Meleon profile from two differents, and if it works, there is just a problems with bookmarks.html, K-Meleon always ask for it's location. This use is a little special, and it has needed to create a new user group, and add it to the two users, and then set it for all the K-Meleon profile folder (recursive)
But I admit it's a very special use , and commonly, I think that folders are located in ~/.wine/drive_c/users/'username'/Applications Datas/K-Meleon/.....
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Mail : alain [dot] aupeix [at] wanadoo [dot] fr
Ubuntu 12.04 - Gramps 3.4.9 - Harbour 3.2.0 - Hwgui 2.20-3 - K-Meleon 76.0 rc